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Our research group is interested in how social psychological and sociocultural phenomena influence student learning, development, and success. Our group primarily studies research experiences, including undergraduate and graduate research, as a context for teaching, learning, and mentoring. In…
Our research concerns the mechanism and consequences of Ty1 retrotransposition in the budding yeast Saccharomyces. The Ty1 life cycle resembles that of retroviruses except transposition is not infectious. Ty1 GAG and POL genes encode the structural and enzymatic proteins required for…
We are an inter-disciplinary research group using concepts and techniques from diverse disciplines including biophysics, biochemistry, and bioinformatics to understand how proteins, the molecular machines of life, work. Our current efforts are focused on protein kinases, a large and diverse…
I investigate how to support college biology instructors as they incorporate reformed teaching strategies into their practice. Reformed teaching strategies are strategies that have been shown to improve student outcomes, such as conceptual understanding, problem solving, retention, engagement,…
The work in my laboratory deals with the biosynthesis of heme and it regulation. Heme is an essential cofactor for almost all living organisms and participates in a variety of reactions including the regulation central metabolic processes, oxygen binding and transport and reduction/oxidation…
We are using biochemical, cell biological, genetic, and molecular approaches in conjunction with the yeast system to better understand the function of enzymes involved in the production of isoprenylated proteins. Examples of isoprenylated proteins include the Ras family of oncoproteins, Ras-…
Our laboratory examines how post-translational modifications (primarily glycosylation) increase functional diversity of proteins. We are focused on congenital disorders of O-glycosylation that includes forms of X-linked intellectual disability (defects in the O-GlcNAc pathway; OGT-CDG,…
My lab studies the relationship between protein structure and function, and specifically how enzyme activity is regulated. To do this, we use a combination of techniques, including X-ray crystallography, transient and steady state kinetic, sedimentation velocity and other biophysical tools.…
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