Labs

Our current research focuses mainly on hyperthermophiles, which are microorganisms that grow near 100°C, and on the roles of metals in microbial metabolism.  In a basic science project, we are using the archaeon Pyrococcus furiosus, which grows up to 103°C, to study the structure and evolution of…
Darvill's research focuses on structurally characterizing the five major noncellulosic carbohydrates of plant primary cell walls homogalacturonan, rhamnogalacturonan I and II, xyloglucan, and glucuronoarabinoxylan. Plant primary cell walls control the rate and direction of cell growth that…
Biosynthesis and Biological Function of Pectin
What is Pectin?
The cell wall of plants is a polysaccharide and protein rich macromolecular structure that is essential for plant form and function. It is also the meeting point between the plant and its symbionts or pathogens. Pectin is a major…
We study CRISPR-Cas immune systems that protect prokaryotes from viruses and provide research tools for important biotechnology and biomedical applications
CRISPR-Cas systems are recently discovered RNA-based adaptive immune systems that control invasions of viruses and other mobile genetic…
Dr. York's diverse research interests include the development and application of spectroscopic and computational methods for the structural and conformational analysis of complex carbohydrates, the development of bioinformatics tools to study the roles of carbohydrates in living systems, and the…