Labs

Our current research focuses mainly on hyperthermophiles, which are microorganisms that grow near 100°C, and on the roles of metals in microbial metabolism.  In a basic science project, we are using the archaeon Pyrococcus furiosus, which grows up to 103°C, to study the structure and evolution of…
The three dimensional structures of proteins or protein complexes can provide important clues concerning protein function and mechanism of action on a molecular level. The Rose laboratory is interested in using molecular biology coupled with X-ray crystallography and other biophysical techniques to…
The Scott group conducts research in the general areas of biophysical chemistry. Major current research projects include the use of X-ray absorption spectroscopy to study the structure of metals in biological systems, including metal binding sites in metallosensors and metalloregulators, as well as…
We study CRISPR-Cas immune systems that protect prokaryotes from viruses and provide research tools for important biotechnology and biomedical applications
CRISPR-Cas systems are recently discovered RNA-based adaptive immune systems that control invasions of viruses and other mobile genetic…